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Item number: Cay13812-500

17beta-hydroxy Wortmannin is an analog of wortmannin. It irreversibly binds phosphoinositide 3-kinase (PI3K) and potently blocks fMLP-stimulated respiratory burst in neutrophils (IC50 = 5 nM). 17beta-hydroxy Wortmannin inhibits recombinant PI3K and mTOR (IC50 = 2.7 and 193 nM, respectively) and prevents the growth...

Keywords:	17beta-hydroxy-11-(acetyloxy)-1S,6bR,7,8,9aS,10,11R,11bR-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-3H-furo[4,3,2-de]inde...
Application:	PI3K inhibitor
CAS	58053-83-1
MW:	430.4 D

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17beta-Hydroxywortmannin

Item number: TGM-T84510-10mg

Description: 17beta-Hydroxywortmannin is an orally active phosphatidylinositol-3-kinase (PI-3-kinase) inhibitor, exhibiting an IC50 of 0.5 nM and notably suppresses osteoclast resorption at an IC50 of 10 nM. Additionally, it demonstrates antitumor activity. Target: Others. Smiles:...

Keywords:	Wortmannin-17beta-ol
Application:	PI3K inhibitor
CAS	58053-83-1
MW:	430.45 D

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