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Norfluoxetine (hydrochloride)
Norfluoxetine (hydrochloride)

Item number: Cay15900-1

Norfluoxetine is an active metabolite of the antidepressant fluoxetine. It is formed from fluoxetine by the cytochrome P450 (CYP) isoforms CYP2C9, CYP2C19, and CYP3A. Norfluoxetine inhibits serotonin (5-HT) uptake in rat brain synaptosomal membrane preparations (Ki = 44.7 nM) and isolated human platelets (IC50 = ~15...
Keywords: Desmethylfluoxetine, gamma-[4-(trifluoromethyl)phenoxy]-benzenepropanamine, monohydrochloride
Application: Serotonin uptake inhibitor
CAS 57226-68-3
MW: 331.8 D
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