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Paxilline
Paxilline

Item number: Cay11345-5

Paxilline is an indole diterpene from fungi which potently and reversibly inhibits large conductance Ca2+-activated K+ (BKCa) channels, as shown in patch clamp (Ki = 1.9 nM) and whole smooth muscle cell studies (Ki = 35.7 nM). It also enhances the binding of charybdotoxin (Cay-24115), a peptidyl neurotoxin, to BKCa...
Keywords: 5,6,6a,7,12,12bS,12cR,13,14,14aS-decahydro-4bS-hydroxy-2R-(1-hydroxy-1-methylethyl)-12b,12c-dimethyl-2H-1-benzopyrano[5',6...
Application: BKCa channel inhibitor
CAS 57186-25-1
MW: 435.6 D
From 68.00€ *
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Paxilline
Paxilline

Item number: AG-CN2-0167-M001

Off-white solid. Soluble in DMSO, methanol or ethanol. Tremorgenic, Potent, selective and reversible inhibitor of high-conductance calcium-activated potassium (BKCa) channels, Reversible inhibitor of inositol 1,4,5-trisphosphate receptor (InsP(3)), Sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) inhibitor, Liver X...
Keywords: BRN 5317894, NSC 658707
Application: High-conductance calcium-activated potassium (BKCa) channel inhibitor, SERCA inhibitor
CAS 57186-25-1
MW: 435,6 D
From 55.00€ *
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Paxilline
Paxilline

Item number: LKT-P0392.1

A tremorgenic indole alkaloid that selectively blocks high-conductance Ca2??? K???.
Application: BKCa channel inhibitor
CAS 57186-25-1
MW: 435.56 D
From 128.00€ *
Review