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Maytansinol
Item number: Cay29228-10
Maytansinol is an ansa macrolide originally isolated from P. verrucose that has antimitotic and anticancer activities. It inhibits polymerization and induces depolymerization of bovine brain tubulin with EC50 values of 12 and 43 µM, respectively. Maytansinol inhibits sea urchin egg mitosis when used at a...
| Keywords: | Ansamitocin P-0, Antibiotic C-15003P0, NSC 239386, 3-O-de[2-(acetylmethylamino)-1-oxopropyl]-maytansine |
| Application: | Ansamacrolide, tubulin polymerization inhibitor, tubulin depolymerization inducer |
| CAS | 57103-68-1 |
| MW: | 565.1 D |
From 187.00€
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Maytansinol
Item number: TGM-T16016-100mg
Description: Maytansinol (Ansamitocin P-0) inhibits microtubule assembly and causes microtubule disassembly in vitro. Target: Apoptosis, Microtubule Associated, ADC Cytotoxin. Smiles: CO[C@@H]1\C=C/C=C(C)\Cc2cc(OC)c(Cl)c(c2)N(C)C(=O)C[C@H](O)[C@]2(C)O[C@H]2[C@H](C)[C@@H]2C[C@@]1(O)NC(=O)O2. References: Edwards A,...
| Keywords: | Ansamitocin P-0 |
| Application: | Ansamacrolide, tubulin polymerization inhibitor, tubulin depolymerization inducer |
| CAS | 57103-68-1 |
| MW: | 565.05 D |
From 30.00€
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