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NSC 87877
NSC 87877

Item number: Cay14908-10

The Src homology region 2 domain-containing phosphatases (SHP) known as SHP-1 and SHP-2 act downstream of receptor and non-receptor tyrosine kinase to modulate signal transduction. NSC 87877 is a cell-permeable, inhibitor of both SHP-1 and SHP-2 (IC50 = 355 and 318 nM, respectively). It is much less effective...
Keywords: 8-hydroxy-7-[2-(6-sulfo-2-naphthalenyl)diazenyl]-5-quinolinesulfonic acid
Application: SHP-1 / SHP-2 inhibitor
CAS 56990-57-9
MW: 459.4 D
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