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YM-254890
YM-254890

Item number: AG-CN2-0509-MC05

Off-white solid. Soluble in DMSO (10mg/ml). Cyclic depsipeptide composed of unique amino acids differing from normal amino acids, Membrane permeable, potent and selective Galphaq family inhibitor, Inhibits the signal transduction of Galphaq, Galpha11 and Galpha14 (IC50=0.095&mu,M) by blocking the exchange of GDP for...
Keywords: QS 3666A
Application: G alpha q family inhibitor
CAS 568580-02-9
MW: 960,1 D
From 220.00€ *
Review
YM-254890
YM-254890

Item number: Cay29735-1

YM-254890 is cyclic depsipeptide originally isolated from Chromobacterium and an inhibitor of Galphaq/11. It inhibits Galphaq/11-mediated intracellular calcium mobilization induced by 2MeSADP or methacholine in C6-15 cells expressing the purinergic P2Y1 receptor (IC50 = 0.15 µM) and in CHO cells expressing M1...
Keywords: N-acetyl-L-threonyl-(alphaR)-alpha-hydroxybenzenepropanoyl-2,3-didehydro-N-methylalanyl-L-alanyl-N-methyl-L-alanyl-(3R)-3-...
Application: Cyclic depsipeptide Galphaq/11 inhibitor
CAS 568580-02-9
MW: 960.1 D
423.00€ *
Review