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AZD 2098
Item number: Cay27633-1
AZD 2098 is a CC chemokine receptor 4 (CCR4) antagonist. AZD 2098 inhibits CCL22-induced calcium flux in CHO cells expressing human recombinant CCR4 (IC50 = 31.6 nM) and CCL22- and CCL17-mediated Th2 cell chemotaxis (IC50 = 501.2 nM for both). AZD 2098 is selective for CCR4 over CXCR1, CXCR2, CCR1, CCR2b, CCR5,...
| Keywords: | 2,3-dichloro-N-(3-methoxy-2-pyrazinyl)-benzenesulfonamide |
| Application: | CCR4 antagonist |
| CAS | 566203-88-1 |
| MW: | 334.2 D |
From 49.00€
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AZD2098
Item number: TGM-T4300-100mg
Description: AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor used for asthma research. Target: CCR. Smiles: COc1nccnc1NS(=O)(=O)c1cccc(Cl)c1Cl. References: Asher Mullard. Cancer charity sees success re-prioritizing industry's shelved compounds. Nature Reviews Drug Discovery 13, 319-321 (2014)
| Application: | CCR4 antagonist |
| CAS | 566203-88-1 |
| MW: | 334.18 D |
From 30.00€
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