Description: Acarbose (BAY g 5421) is an inhibitor of alpha-Glucosidases with antihyperglycemic activity. Target: Glucosidase. Smiles: O([C@@H]1[C@@H](CO)O[C@H](O[C@@H]([C@@H]([C@H](C=O)O)O)[C@@H](CO)O)[C@H](O)[C@H]1O)[C@@H]2[C@H](O)[C@@H](O)[C@H](N[C@H]3C=C(CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](C)O2. References:...

White to yellowish powder. An alpha-glucosidase inhibitor that inhibits sucrose digestion in rats. It has been found to reduce the risk of cardiovascular disease and hypertension.

Acarbose is an oligosaccharide and inhibitor of alpha-glucosidases (IC50s = 0.16 and 2.9 µM for maltase and sucrase, respectively). It also activates phosphorylase kinase in a cell-free assay when used at a concentration of 250 µM. Acarbose (40 mg/kg in the diet) decreases urine levels of glucose and glycosylated...