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PRIMA-1
Item number: Cay63520-1
Mutations in the p53 tumor suppressor are found in many different neoplastic cells. PRIMA-1 restores sequence-specific DNA binding and transactivational activity to mutant p53 proteins at relatively high µM to mM concentrations. It is therefore a unique anti-oncogenic substance, working as a re-activator of the...
| Keywords: | 2,2-bis(hydroxymethyl)-3-quinuclidinone |
| Application: | Anti-oncogenic substance |
| CAS | 5608-24-2 |
| MW: | 185.2 D |
From 29.00€
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PRIMA-1
Item number: TGM-T6954-100mg
Description: PRIMA-1 (NSC-281668) is a mutant p53 reactivator that induces apoptosis and inhibits the growth of human tumors with mutant p53. Target: Apoptosis, Autophagy, Ferroptosis, Others. Smiles: OCC1(CO)N2CCC(CC2)C1=O. References: Izetti P, et al. Invest New Drugs. 2014, 32(5):783-94.
| Keywords: | 2,2-Bis(hydroxymethyl)-3-quinuclidinone, NSC-281668, PRIMA 1 |
| Application: | Anti-oncogenic substance |
| CAS | 5608-24-2 |
| MW: | 185.22 D |
From 45.00€
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