2 products were found matching "552325-16-3"!
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A-443654
Item number: Cay16499-500
Three related forms of the kinase Akt (1, 2, 3, also known as protein kinase B isoforms PKBalpha, beta, gamma) modulate cell proliferation, metabolism, and survival as well as angiogenesis. A-443654 is an inhibitor of Akt (Ki = 160 pmol/L for all three isoforms) that interferes with mitotic progression and bipolar...
| Keywords: | alphaS-[[[5-(3-methyl-1H-indazol-5-yl)-3-pyridinyl]oxy]methyl]-1H-indole-3-ethanamine |
| Application: | Akt inhibitor |
| CAS | 552325-16-3 |
| MW: | 397.5 D |
From 92.00€
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A-443654
Item number: AG-CR1-3663-M001
White to off-white solid. Soluble in DMSO (15mg/ml), ethanol (10mg/ml) or DMF (20mg/ml). Potent and selective Akt inhibitor (Ki=160pmol/L for all three isoforms PKBalpha, PKBbeta and PKBgamma), DYRK1A inhibitor (IC50=10nM). Inhibits other kinases, including PRK2, MSK1 and DYRK3 at low nM range as well, Interferes...
| Keywords: | (S)-1-(1H-Indol-3-yl)-3-((5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl)oxy)propan-2-amine |
| Application: | Potent and selective Akt inhibitor |
| CAS | 552325-16-3 |
| MW: | 397,5 D |
From 105.00€
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