- Search results for 55224-94-7
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2 products were found matching "55224-94-7"!
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Item number: Cay11912-10
AP-18 is a channel blocker which reversibly inhibits TRPA1 (IC50s = 3.1 and 4.5 µM, human and mouse, respectively). It has minimal effect on TRPV1-4 or TRPM8. AP-18 has been used to study TRPA1 signaling in mice and rats as well as in vitro.Formal Name: 4-(4-chlorophenyl)-3-methyl-3-buten-2-one, oxime. CAS Number:...
| Keywords: | 4-(4-chlorophenyl)-3-methyl-3-buten-2-one, oxime |
| Application: | TRPA1 inhibitor |
| CAS | 55224-94-7 |
| MW: | 209.7 D |
From 89.00€
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Item number: TGM-T21543-100mg
Description: AP-18 is a potent and selective TRPA1 inhibitor. AP-18 inhibits activation of TRPA1 induced by 50 µM Cinnamaldehyde with an IC50 of 3.1 µM and 4.5 µM for human and mouse TRPA1, respectively. AP-18 could reverse complete Freund's adjuvant (CFA)-induced mechanical hyperalgesia in mice. AP-18 could...
| CAS | 55224-94-7 |
| MW: | 209.67 D |
From 40.00€
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