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BMS-345541 hydrochloride
Item number: TGM-T8542-100mg
Description: BMS-345541 hydrochloride is a selective IKK inhibitor, targeting IKK2 and IKK1 with IC50 values of 0.3 µM and 4 µM, respectively. Target: IkappaB/IKK. Smiles: Cl.Cc1cnc2c(NCCN)nc3ccc(C)cc3n12. References: Yang J, et al. BMS-345541 targets inhibitor of kappaB kinase and induces apoptosis in melanoma:...
| Application: | Cell permeable IKK-alpha/beta inhibitor |
| CAS | 547757-23-3 |
| MW: | 291.78 D |
From 34.00€
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BMS 345541 (hydrochloride)
Item number: Cay16667-1
BMS 345541 is a cell permeable inhibitor of the IkappaB kinases IKKalpha and IKKbeta (IC50s = 4 and 0.3 µM). It is without effect against a panel of other serine/threonine and tyrosine kinases at 100 µM. BMS 345541 inhibits signaling through nuclear factor-kappaB (NF-kappaB) both in cells and in vivo, showing...
| Keywords: | IKK Inhibitor III, N1-(1,8-dimethylimidazo[1,2-a]quinoxalin-4-yl)-1,2-ethanediamine, bis(2,2,2-trifluoroacetate) |
| Application: | Cell permeable IKK-alpha/beta inhibitor |
| CAS | 547757-23-3 |
| MW: | 291.8 D |
From 61.00€
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