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Item number: Cay15626-5

ML-204 selectively blocks transient receptor potential canonical 4 (TRPC4) channels (IC50s = 0.96 and 2.6 µM in fluorescent and electrophysiological assays, respectively). It exhibits 19-fold selectivity against TRPC6 and 9-fold selectivity against TRPC5 and does not affect TRPV1, TRPV3, TRPA1, or TRPM8 channels at...

Keywords:	2-piperidino-Lepidine, CID-230710, NSC 25850, 4-methyl-2-(1-piperidinyl)-quinoline
Application:	TRPC4 blocker
CAS	5465-86-1
MW:	226.3 D

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ML204

Item number: TGM-T2298-100mg

Description: ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels. Target: TRP/TRPV Channel. Smiles: Cc1cc(nc2ccccc12)N1CCCCC1. References: Miller M, et al. J Biol Chem. 2011 Sep 23,286(38):33436-46.

CAS	5465-86-1
MW:	226.32 D

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