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Item number: Cay16321-1

Vacquinols are a new class of quinine-derivatives that stimulate death in glioblastoma cells by massive macropinocytotic vacuolization, ATP depletion, and cytoplasmic membrane rupture. A key effector of vacquinols is MAPK kinase 4 (MKK4). Vacquinol-1 is an activator of MKK4-dependent macropinocytotic cell death in...

Keywords:	NSC 13316, 2-(4-chlorophenyl)-alpha-2-piperidinyl-4-quinolinemethanol
Application:	MKK4 activator
CAS	5428-80-8
MW:	352.9 D

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Vacquinol-1

Item number: TGM-T7008-100mg

Description: Vacquinol-1 is an MKK4 activator, which rapidly and selectively induces glioma cell death. Target: JNK. Smiles: C(O)(C=1C2=C(N=C(C1)C3=CC=C(Cl)C=C3)C=CC=C2)C4CCCCN4. References: Kitambi SS, et al. Cell. 2014, 157(2), 313-328.

Keywords:	Vacquinol 1
Application:	MKK4 activator
CAS	5428-80-8
MW:	352.86 D

From 183.00€ *

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