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COVID-19 Research

Item number: Cay30729-10

Cinanserin is a serotonin (5-HT) receptor antagonist. It inhibits 5-HT-induced effects on isolated rat uterus but not guinea pig ileum. Cinanserin inhibits 5-HT-induced gross excitation, gastric mucosal erosion, and anaphylactoid edema in mice and rats. Cinanserin (12 and 36 mg/kg, i.p.) impairs acquisition of a...

Keywords:	SQ 10,643, N-[2-[[3-(dimethylamino)propyl]thio]phenyl]-3-phenyl-2-propenamide, monohydrochloride
Application:	Antiviral, 5-HT receptor antagonist
CAS	54-84-2
MW:	376.9 D

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Cinanserin hydrochloride

Item number: TGM-T14968-100mg

Description: Cinanserin hydrochloride (SQ 10643), a high-affinity antagonist of the 5-HT2 receptor (Ki: 41 nM), is also a 3C-like protease inhibitor of severe acute respiratory syndrome coronavirus. Target: 5-HT Receptor, Influenza Virus. Smiles: Cl.CN(C)CCCSc1ccccc1NC(=O)C=Cc1ccccc1. References: Chen L, et al....

Keywords:	SQ 10643
Application:	Targets SARS coronavirus 3C-like proteinase [EC:3.4.22.69] (nsp5)
CAS	54-84-2
MW:	376.94 D

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