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Aminopterin
Item number: Cay21802-50
Aminopterin is a synthetic folic acid (Cay-20515) derivative whose metabolite is a competitive inhibitor of dihydrofolate reductase, which is a cofactor for nucleic acid synthesis. Aminopterin has anticancer and immunosuppressive properties. Formulations containing it have been used for pediatric leukemia though...
| Keywords: | 4-amino Folic Acid, 4-amino PGA, APGA, NSC 739, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid |
| Application: | Dihydrofolate reductase inhibitor prodrug |
| CAS | 54-62-6 |
| MW: | 440.4 D |
From 43.00€
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Aminopterin
Item number: LKT-A5001.100
Solid. An inhibitor of dihydrofolate reductase, shown to induce apoptosis in a mouse HGPRT(-) myeloma cell line.
| Application: | Dihydrofolate reductase inhibitor |
| CAS | 54-62-6 |
| MW: | 440,41 D |
From 333.00€
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