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Item number: Cay40120-100

PFI-90 is an inhibitor of lysine demethylases (KDMs). It inhibits KDM3B, KDM4B, KDM5A, and KDM6B by 46.8 to 87.1% when used at a concentration of 10 µM. PFI-90 induces cell death in SJSA-1 osteosarcoma and TC-32 Ewing's sarcoma cancer cells (IC50s = 2 and 1 µM, respectively).Formal Name: 2-(2-pyridinyl)hydrazide,...

Keywords:	2-(2-pyridinyl)hydrazide, 2-pyridinecarboxylic acid
Application:	KDM (lysine demethylase) inhibitor
CAS	53995-62-3
MW:	214.2 D

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PFI-90

Item number: TGM-T9243-1mL

Description: PFI-90, a selective histone demethylase (KDM3B) inhibitor, targets PAX3-FOXO1 action and demonstrates potential antitumor activity. It induces apoptosis and myogenic differentiation, leading to increased cell death. Target: Histone Demethylase, Others. Smiles: O=C(NNc1ccccn1)c1ccccn1. References: KHAN,...

Application:	KDM (lysine demethylase) inhibitor
CAS	53995-62-3
MW:	214.22 D

From 33.00€ *

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