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Item number: TGM-T4566-100mg

Description: Lodoxamide (Lodoxamidum) is an antiallergic drug acting as a mast-cell stabilizer. It is effective in the treatment of asthma and allergic conjunctivitis. Target: Histamine Receptor, GPR. Smiles: OC(=O)C(=O)Nc1cc(cc(NC(=O)C(O)=O)c1Cl)C#N. References: Watt GD, et al. Protective effect opf lodoxamide...

Keywords:	Lodoxamidum
Application:	Antiallergic, Antiasthmatic
CAS	53882-12-5
MW:	311.63 D

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Lodoxamide

Item number: Cay23994-25

Lodoxamide is a potent agonist of GPR35 with an EC50 value of 1.61 nM in a beta-arrestin-2 interaction assay using CHO-K1 cells expressing the human receptor. It inhibits histamine release induced by compound 48/80 (Cay-22173), anti-IgE, or A23187 (Cay-11016) in isolated rat peritoneal mast cells (IC50s = 0.1-50 µM)...

Keywords:	2,2'-[(2-chloro-5-cyano-1,3-phenylene)diimino]bis[2-oxo-acetic acid]
Application:	GPR35 agonist
CAS	53882-12-5
MW:	311.6 D

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