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Item number: Cay29760-10

GMQ is an activator of acid-sensing ion channel 3 (ASIC3). It evokes rapid inward currents with little desensitization in CHO cells expressing ASIC3 (EC50 = 67 µM at neutral pH). It is also an inhibitor of the GABAA receptor (IC50 = 0.39 µM in primary rat hippocampal neurons). GMQ has stimulatory effects on...

Keywords:	N-(4-methyl-2-quinazolinyl)-guanidine, monohydrochloride
Application:	ASIC3 activator
CAS	5361-15-9
MW:	237.7 D

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GMQ hydrochloride

Item number: TGM-T8617-100mg

Description: GMQ hydrochloride (NSC-403387 hydrochloride) is a potent and selective acid-sensing ion channel (ASIC) modulator. It activates ASIC3 channels under neutral pH and blocks acid-induced maximal peak current. Target: Others, Sodium Channel. Smiles: Cl.Cc1nc(NC(N)=N)nc2ccccc12. References: So, Edmund,...

Keywords:	NSC 403387 hydrochloride
Application:	ASIC3 activator
CAS	5361-15-9
MW:	237.69 D

From 36.00€ *

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