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(-)-Bicuculline methochloride
Item number: TGM-T12044-10mg
Description: (-)-Bicuculline methochloride is a potent antagonist of GABAA receptor. Target: GABA Receptor. Smiles: C[N+]1(C)[C@@]([C@@]2(C3=C(C(=O)O2)C4=C(C=C3)OCO4)[H])(C5=C(C=C6C(=C5)OCO6)CC1)[H].[Cl-]. References: Seutin V, et al. Recent advances in the pharmacology of quaternary salts of bicuculline. Trends...
| Keywords: | l-Bicuculline methochloride |
| CAS | 53552-05-9 |
| MW: | 417.84 D |
From 159.00€
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(-)-Bicuculline methochloride
Item number: Cay27802-5
(-)-Bicuculline methochloride is an enantiomer of the GABA antagonist (+)-bicuculline methochloride. It increases the firing rate in rat cortical neurons similar to the (+) isomer but lacks GABA antagonist activity. (-)-Bicuculline methochloride inhibits sodium-independent GABA receptor binding with an IC50 value of...
| Keywords: | (5R)-5-[(6S)-6,8-dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl]-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquino... |
| Application: | GABA-A receptor antagonist |
| CAS | 53552-05-9 |
| MW: | 417.8 D |
From 88.00€
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