Description: 7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) is a 5-Hydroxytryptamine Receptor Subtype 1E (HTR1E) antagonist, a Galanin Receptor 2 (GALR2) antagonist, and a hydroxysteroid (17-beta) dehydrogenase 4 (HSD17B4) inhibitor with an activity value of 21 µM. Target: 5-HT Receptor. Smiles:...

This compound is the precursor for a variety of AFC enzyme substrates. It is also used as a calibration standard for AFC-based enzyme substrates.

Liquid. A fluorogenic standard useful for quantitating assays monitoring 7-amino-4-trifluoromethylcoumarin (AFC) release such as those utilizing ubiquitin-AFC. The concentration of the AFC released can be calculated from a standard curve prepared with AFC standards.

Liquid. Chemical. CAS: 53518-15-3. Formula: C10H6F3NO2. MW: 229.2. Synthetic. A fluorogenic standard useful for quantitating assays monitoring 7-amino-4-trifluoromethylcoumarin (AFC) release such as those utilizing ubiquitin-AFC. The concentration of the AFC released can be calculated from a standard curve prepared...

7-Amino-4-trifluoromethylcoumarin (AFC) is used in the synthesis of substrates for the fluorometric assay of proteolytic enzymes in biological fluids and therefore the precursor for a variety of AFC enzyme substrates. It is a fluorogenic standard useful as a calibration standard for AFC-based enzyme substrates and...