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PIT-1
Item number: Cay10728-10
PtdIns-(3,4,5)-P3 (PIP3) serves as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains such as phosphatidylinositol 3-kinase (PI3K) or PTEN. Protein binding to PIP3 is important for cytoskeletal rearrangement and membrane trafficking and initiates an intricate signaling...
| Keywords: | N-[[(3-chloro-2-hydroxy-5-nitrophenyl)amino]thioxomethyl]-benzamide |
| Application: | PI3K-PDK1-Akt-dependent phosphorylation inhibitor |
| CAS | 53501-41-0 |
| MW: | 351.8 D |
From 30.00€
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PIT-1
Item number: TGM-T23163-5mg
Description: PIT-1 is a selective PIP3 antagonist that inhibits cancer cell survival and induces apoptosis by inhibiting PIP3-dependent PI3K/Akt signalling and the PH structural domain of Akt. Target: PI3K, Others, Apoptosis, Akt. Smiles: O=C(NC(=S)NC1=CC(=CC(Cl)=C1O)N(=O)=O)C=2C=CC=CC2
| Keywords: | PIT1 |
| CAS | 53501-41-0 |
| MW: | 351.76 D |
From 29.00€
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