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ML-090
Item number: Cay15172-10
NADPH oxidase 1 (NOX1) generates reactive oxygen species (ROS) in colon epithelial cells that interacts with both pathogenic and normal bacteria. Excess ROS production, however, is associated with damage to the intestinal mucosa, inflammatory bowel disease, and prostate cancer. ML-090 is the first identified...
| Keywords: | CCG-44699, CID-616479, Fluoflavin, NSC 179821, 5,12-dihydro-quinoxalino[2,3-b]quinoxaline |
| Application: | NADPH oxidase 1 (NOX-1) inhibitor |
| CAS | 531-46-4 |
| MW: | 234.3 D |
From 51.00€
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ML-090
Item number: TGM-T22990-5mg
Description: ML-090 is NOX1-specific inhibitor(IC50 = 90 nM) which is >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50s >10 µM). Target: NADPH-oxidase, Others. Smiles: N1c2ccccc2Nc2nc3ccccc3nc12. References: Brown SJ, et al. Probe Report for NOX1 Inhibitors. 2009 Apr 23 [updated 2010 Sep 2]. In: Probe...
| Keywords: | Fluoflavine |
| CAS | 531-46-4 |
| MW: | 234.26 D |
29.00€
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