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Item number: Cay10010302-10

DRB is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II (IC50 range of 4-10 µM), Cdk7 (IC50 = ~20 µM), Cdk8 (IC50 = ~20 µM), and Cdk9 (IC50 = 3 µM). Through inhibition of certain CTD kinases, DRB inhibits an elongation step during RNA polymerase II...

Keywords:	Benzimidazole, NSC 401575, 5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole
Application:	CTD kinase inhibitor
CAS	53-85-0
MW:	319.1 D

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