3 products were found matching "53-19-0"!
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Mitotane
Item number: TGM-T1199-100mg
Description: Mitotane (NCI-C04933) is a derivative of the insecticide DICHLORODI PHENYLDICH LOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression. Target: AChR, Apoptosis....
| Keywords: | Mitotan, NCI-C04933, o,p'-DDD, 2,4'-DDD |
| Application: | Targets steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase (CYP17A) |
| CAS | 53-19-0 |
| MW: | 320.04 D |
From 31.00€
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Mitotane
Item number: Cay18651-100
Mitotane is an inhibitor of steroidogenesis. It decreases secretion of cortisol (Cay-20739) and 17-hydroxy progesterone (Cay-33154) from H295R adrenocortical carcinoma cells when used at a concentration of 50 µM. Mitotane also inhibits mitochondrial complex IV, also known as cytochrome c oxidase, activity in H295R...
| Keywords: | o,p'-DDD, NSC 38721, 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]-benzene |
| Application: | Steroidogenesis inhibitor |
| CAS | 53-19-0 |
| MW: | 320 D |
From 44.00€
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Mitotane
Item number: LKT-M3576.100
An adrenal cyto-toxic agent used to treat adrenocartical tumors.
| Application: | Cytotoxic agent |
| CAS | 53-19-0 |
| MW: | 320,04 D |
From 101.00€
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