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Item number: Cay9000487-5

Mutations in the p53 tumor suppressor are found in many different neoplastic cells. PRIMA-1 (Cay-63520) is a unique anti-oncogenic substance that re-activates the apoptotic function of mutant p53 via conformational modulation of function-specific epitopes. PRIMA-1MET is a methylated derivative of PRIMA-1 that...

Keywords:	APR 246, 2-(hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one
Application:	Mutant p53 apoptotic function re-activator
CAS	5291-32-7
MW:	199.3 D

From 102.00€ *

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Eprenetapopt

Item number: TGM-T4414-5mg

Description: Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells. PRIMA-1MET also targets the selenoprotein thioredoxin reductase 1 (TrxR1), a key regulator of cellular redox balance. Target: Ferroptosis, p53, Autophagy, Apoptosis, Others....

Keywords:	APR-246, PRIMA-1Met
Application:	Antineoplastic, Hypomethylating agent
CAS	5291-32-7
MW:	199.25 D

From 64.00€ *

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