Description: N-Oxalylglycine (Oxalylglycine) is a cell permeable inhibitor of alpha-ketoglutarate-dependent enzymes. Target: Others. Smiles: OC(=O)CNC(=O)C(O)=O. References: Al-Qahtani, K., Jabeen, B., Sekirnik, R., Riaz, N., Claridge, T., Schofield, C., & McCullagh, J. The broad spectrum 2-oxoglutarate oxygenase...

The jumonji domain-containing protein 2 (JMJD2) subfamily of histone demethylases have been shown to catalyze demethylation of the methylated forms of histone 3 lysine 9 (H3K9) and H3K36 in vitro and in cells. Because histone demethylases are implicated in certain diseases, including cancer, selective inhibitors are...