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Item number: Cay64970-1

2-Aminoethyl diphenylborinate (2-APB) is a modulator of intracellular calcium levels and transient receptor potential (TRP) channels. It inhibits calcium release induced by inositol-1,4,5-triphosphate (IP3) in rat cerebellar microsomes (IC50 = 42 µM) without affecting IP3 binding to its receptor. 2-APB inhibits...

Keywords:	2,2-diphenyl-1,3,2-oxaza-borolidine internal salt
Application:	Ins(1,4,5)-P3 receptor antagonist
CAS	524-95-8
MW:	225.1 D

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2-Aminoethyl diphenylborinate

Item number: TGM-T4693-100mg

Description: 2-Aminoethyl diphenylborinate (2-APB) is a chemical compound that inhibits IP3 receptors and TRP channels, though it activates TRPV1, TRPV2, and TRPV3 at higher concentrations. Target: Calcium Channel, TRP/TRPV Channel. Smiles: NCCOB(c1ccccc1)c1ccccc1. References: Bai et al (2006) Block of specific gap...

Keywords:	2-Aminoethoxydiphenyl borate, 2-APB
Application:	TRPV1/2/3 blocker
CAS	524-95-8
MW:	225.09 D

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