Haloperidol is a typical antipsychotic and dopamine D2-like receptor antagonist (Kis = 0.6, 0.2, and 22 nM, for D2, D3, and D4 receptors, respectively). It also acts as an inverse agonist at dopamine D2 and D3 receptors (IC50s = 0.8 and 0.6 nM, respectively). Haloperidol also binds to alpha1- and alpha2- adrenergic...

Butyrophenone, sigma2 agonist, alpha1-adrenergic, D2, 5-HT2A, sigma1 antagonist.

Haloperidol (CRM) (Cay-40431) is a certified reference material categorized as a typical antipsychotic. Haloperidol inhibits stereotypic behavior induced by apomorphine or amphetamine in rats. It also inhibits apomorphine-induced decreases in prepulse inhibition of the acoustic startle response in rats. Haloperidol...

Description: Haloperidol (Serenace) is a highly potent neuroleptic by relieving nervous through the depression of nerve function. In addition, haloperidol has shown about 50-fold efficacy than chlorpromazine, another antipsychotic drug. Haloperidol has some potencies in the treatment of delusions and hallucinations....