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Item number: Cay21189-1

TNP is a cell-permeable inhibitor of inositol-1,4,5-trisphosphate 6-kinase 1 (IP6K1, IC50 = 0.55 µM, Ki = 0.24 µM) and IP3K (IC50 = 10.2 µM, Ki = 4.3 µM) that binds to the ATP-binding sites of both enzymes. TNP reduces IP7 and IP8 levels (IC50s = ~3 and 1 µM, respectively) and inhibits insulin release in MIN6...

Keywords:	IP3K Inhibitor, IP6K Inhibitor, N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-9H-purine-2,6-diamine
Application:	IP3K inhibitor
CAS	519178-28-0
MW:	443.4 D

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