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UMI-77
Item number: TGM-T6034-100mg
Description: UMI-77, a specific Mcl-1 inhibitor (Ki: 490 nM), has selectivity over other members of Bcl-2 family. Target: BCL. Smiles: OC(=O)CSc1cc(NS(=O)(=O)c2ccc(Br)cc2)c2ccccc2c1O. References: Abulwerdi F, et al. Mol Cancer Ther. 2014, 13(3), 565-575.
| Keywords: | UMI 77, UMI77 |
| Application: | Mcl-1 inhibitor |
| CAS | 518303-20-3 |
| MW: | 468.34 D |
From 37.00€
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UMI-77
Item number: Cay19148-1
Myeloid cell leukemia-1 (Mcl-1) is a potent anti-apoptotic protein and a member of the pro-survival Bcl-2 family. UMI-77 is a selective Mcl-1 inhibitor with a Ki value of 490 nM and exhibits selectivity over other members of the Bcl-2 family (Kis = 5.3, 23.8, 33.0, and 8.2 µM) for A1/Bfl-1, Bcl-2, Bcl-xL, and Bcl-W,...
| Keywords: | 2-[[4-[[(4-bromophenyl)sulfonyl]amino]-1-hydroxy-2-naphthalenyl]thio]-acetic acid |
| Application: | Mcl-1 inhibitor |
| CAS | 518303-20-3 |
| MW: | 468.3 D |
From 44.00€
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