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Shikonin
Item number: TGM-T1125-100mg
Description: Shikonin (Anchusa acid) is a natural product, a TMEM16A chloride channel inhibitor (IC50=6.5 µM) and selective PKM2 inhibitor. Shikonin exhibits antitumor, anti-inflammatory and wound healing activities. Target: TNF, PKM, Chloride channel, HIV Protease, NF-kappaB. Smiles:...
| Keywords: | (+)-Shikonin, Isoarnebin 4, NSC 252844, Alkanna Red, C.I. 75535, Anchusa acid |
| CAS | 517-89-5 |
| MW: | 288.3 D |
From 30.00€
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Shikonin
Item number: Cay14751-5
Shikonin is a naturally occurring naphthoquinine isolated from the dried root of L. erythrorhizon, an herb used in traditional Chinese medicine. It increases glucose uptake by adipocytes and myocytes and inhibits the activity of phosphatase and tensin homolog (PTEN, IC50 = 2.7 µM). It inhibits glycolysis in cancer...
| Keywords: | C.I. 75535, Isoarnebin 4, NSC 252844, 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methyl-3-penten-1-yl]-1,4-naphthalenedione |
| Application: | PTEN inhibitor |
| CAS | 517-89-5 |
| MW: | 288.3 D |
From 44.00€
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COVID-19 Research
Shikonin
Item number: AG-CN2-0487-M010
Purple red solid. Soluble in DMSO or DMF. Sparingly soluble in ethanol, methanol or water. Anticancer compound. Inhibits TNF-alpha-induced and B-16 melanoma-induced angiogenesis, Induces apoptosis and RIP1- and RIP3-dependent necroptosis in several cancer cells. Circumvents cancer antidrug resistance through the...
| Keywords: | (+)-Shikonin, (R)-Shikonin, Tokyo Violet, NSC 252844, Isoarnebin 4, C.I. 75535,... |
| Application: | Antioxidant |
| CAS | 517-89-5 |
| MW: | 288,3 D |
From 55.00€
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