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20(S)-hydroxy Cholesterol
Item number: Cay20103-1
20(S)-hydroxy Cholesterol is an allosteric agonist of the smoothened (Smo) receptor that activates the hedgehog (Hh) signaling pathway with an EC50 value of approxiately 3 µM in a gene transcription reporter assay using NIH3T3 cells. 20(S)-hydroxy Cholesterol is necessary for normal Hh signaling. It induces Smo...
| Keywords: | 20alpha-hydroxy Cholesterol, cholest-5-ene-3beta,20-diol |
| CAS | 516-72-3 |
| MW: | 402.7 D |
From 75.00€
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20(S)-Hydroxycholesterol
Item number: TGM-T10085-100mg
Description: 20(S)-Hydroxycholesterol (20alpha-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo). Target: Smo. Smiles: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@](CCCC(C)C)(C)O)[H])[H]. References: Nachtergaele S, et al. Oxysterols are...
| Keywords: | 20alpha-Hydroxycholesterol |
| CAS | 516-72-3 |
| MW: | 402.65 D |
From 30.00€
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