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(S)-Flurbiprofen
Item number: Cay10004207-100
(S)-Flurbiprofen is the COX-active enantiomer of the non-selective COX inhibitor flurbiprofen (Cay-70250) with IC50 values of 0.48 and 0.47 µM for COX-1 and COX-2, respectively, in guinea pig whole blood. It inhibits the release of 6-keto prostaglandin F1alpha (6-keto-PGF1alpha, Cay-15210) and thromboxane B2 (TXB2,...
| Keywords: | (S)-(+)-2-fluoro-alpha-methyl-4-biphenylacetic acid |
| Application: | COX inhibitor |
| CAS | 51543-39-6 |
| MW: | 244.3 D |
From 145.00€
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(S)-Flurbiprofen
Item number: TGM-T5843L-10mg
Description: Esflurbiprofen is an inhibitor of COX-1 and COX-2. Target: COX, PGE Synthase. Smiles: C[C@H](C(O)=O)c1ccc(c(F)c1)-c1ccccc1. References: B Averbeck, et al. Inflammatory Mediators Do Not Stimulate CGRP Release if Prostaglandin Synthesis Is Blocked by S(+)-flurbiprofen in Isolated Rat Skin. Inflamm Res....
| Keywords: | esflurbiprofen |
| Application: | Targets prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1] (PTGS1, COX1) |
| CAS | 51543-39-6 |
| MW: | 244.26 D |
From 29.00€
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