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1,5-Isoquinolinediol
Item number: Cay14438-100
The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 1,5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1, IC50 = 0.39 µM). It has been used to study the role of PARP1 in both DNA repair and oxidant stress-induced cell death. This compound...
| Keywords: | 1,5-Dihydroxyisoquinoline, NSC 65585, 5-hydroxy-1(2H)-isoquinolinone |
| Application: | PARP1 inhibitor |
| CAS | 5154-02-9 |
| MW: | 161.2 D |
From 48.00€
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1,5-Isoquinolinediol
Item number: AG-CR1-0024-M005
PARP-1 inhibitor, Neuroprotectant, Blocks nitric oxide-induced neuronal toxicity, Potent iNOS (inducible nitric oxide synthase/NOS II) inhibitor, Stimulates homologous recombination.
| Keywords: | 5-Hydroxy-1(2H)-isoquinolinone, 1,5-Dihydroxyisoquinoline |
| Application: | PARP-1 inhibitor |
| CAS | 5154-02-9 |
| MW: | 161,2 D |
From 33.00€
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