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Item number: Cay13948-1

GW 803430 is an antagonist of melanin-concentrating hormone receptor 1 (MCH1, IC50 = 0.5 nM). It reduces cumulative body weight and food intake in diet-induced obese rats when administered at doses of 1 and 3 mg/kg. GW 803430 (10 and 30 mg/kg) decreases marble-burying behavior in mice, indicating anxiolytic...

Keywords:	GW 3430, 6-(4-chlorophenyl)-3-[3-methoxy-4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-thieno[3,2-d]pyrimidin-4(3H)-one
Application:	MCHR1 antagonist
CAS	515141-51-2
MW:	482 D

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GW-803430

Item number: TGM-T15450-100mg

Description: GW-803430 is a potent and selective antagonist of melanin-concentrating hormone receptor 1 (MCH R1) (pIC50: 9.3). GW-803430 is orally active in an animal model of obesity. Target: Others. Smiles: O=C1C2=C(C=C(S2)C3=CC=C(Cl)C=C3)N=CN1C4=CC(OC)=C(OCCN5CCCC5)C=C4. References: Hertzog DL, et al. The...

Keywords:	GW-3430
Application:	MCHR1 antagonist
CAS	515141-51-2
MW:	481.99 D

From 529.00€ *

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