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L-NAME (hydrochloride)
Item number: Cay80210-1
L-NAME requires hydrolysis of the methyl ester by cellular esterases to become a fully functional inhibitor (L-NNA). L-NNA exhibits some selectivity for inhibition of neuronal and endothelial isoforms. It exhibits Ki values of 15 nM, 39 nM, and 4.4 µM for nNOS (bovine), eNOS (human), and iNOS (mouse), respectively....
| Keywords: | L-NG-Nitroarginine methyl ester, N(G)-Nitro-L-arginine methyl ester, N5-[imino(nitroamino)methyl]-L-ornithine, methyl... |
| Application: | NOS inhibitor |
| CAS | 51298-62-5 |
| MW: | 269.7 D |
From 27.00€
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L-NAME hydrochloride
Item number: TGM-T6570-1mL
Description: L-NAME hydrochloride is an inhibitor of nitric oxide synthase (NOS) with an IC50 of 70 µM, and it can be used to induce hypertension and kidney injury models. Target: NO Synthase, NOS. Smiles: Cl.COC(=O)[C@@H](N)CCCNC(=N)N[N+]([O-])=O. References: Rees DD, et al. Br J Pharmacol, 1990, 101(3), 746-752.
| Keywords: | L-NAME HCl , N(G)-Nitro-L-arginine methyl ester , NG-Nitroarginine methyl ester hydrochloride |
| Application: | NOS inhibitor |
| CAS | 51298-62-5 |
| MW: | 269.69 D |
From 30.00€
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