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5-Fluorouracil
5-Fluorouracil

Item number: Cay14416-5

5-Fluorouracil (5-FU) is a prodrug form of the thymidylate synthase inhibitor fluorodeoxyuridylate (FdUMP). It is also converted to the active metabolites FUTP and FdUTP, which induce RNA and DNA damage, respectively. In vivo, 5-FU (15 mg/kg) when administered in combination with docetaxel (Cay-11637) reduces tumor...
Keywords: 5-FU, NSC 19893, Ro 2-9757, U-8953, 5-fluoro-2,4(1H,3H)-pyrimidinedione
Application: Apoptosis inducer, Thymidylate synthase inhibitor
CAS 51-21-8
MW: 130.1 D
From 44.00€ *
Review
5-Fluorouracil
5-Fluorouracil

Item number: LKT-F4480.5

Pyrimidine analog, inhibits thymidylate synthase.
Keywords: Fluorouracil, 5-FU, 2,4-dioxo-5-fluoropyrimidine, 5-Fluoro-2,4(1H,3H)-pyrimidinedione
Application: Apoptosis inducer
CAS 51-21-8
MW: 130,08 D
From 58.00€ *
Review