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MIM1
Item number: TGM-T12041-10mg
Description: MIM1 (Inhibitor of Mcl-1) is an myeloid cell factor 1 (Mcl-1) inhibitor. Target: BCL. Smiles: Cc1cs\c(=N\C2CCCCC2)n1\N=C\c1ccc(O)c(O)c1O. References: Vidomanova E, et al. Microfluidic profiling of apoptosis-related genes after treatment with BH3-mimetic agents in astrocyte and glioblastoma cell lines....
| Keywords: | Inhibitor of Mcl-1 |
| Application: | Selective MCL-1 ligand |
| CAS | 509102-00-5 |
| MW: | 347.43 D |
From 31.00€
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MIM1
Item number: Cay19832-1
MIM1 is an inhibitor of Mcl-1, an antiapoptotic Bcl-2 family protein with a role in cancer. It selectively engages the canonical groove of Mcl-1, inhibiting its ability to bind BH3 domains (IC50 = 4.7 µM). MIM1 induces caspase-3/7 activation and cell death in Mcl-1-dependent leukemia cells.Formal Name:...
| Keywords: | 4-[[[2-(cyclohexylimino)-4-methyl-3(2H)-thiazolyl]imino]methyl]-1,2,3-benzenetriol |
| Application: | Selective MCL-1 ligand |
| CAS | 509102-00-5 |
| MW: | 347.4 D |
From 44.00€
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