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Item number: TGM-T4614-100mg

Description: Ellipticine hydrochloride (NSC-71795 (hydrochloride)) is a potent antineoplastic agent, inhibits DNA topoisomerase II activities. Target: Topoisomerase. Smiles: Cl.Cc1c2[nH]c3ccccc3c2c(C)c2cnccc12. References: Stiborova M, et al. Molecular mechanisms of antineoplastic action of an anticancer drug...

Keywords:	NSC 71795 (hydrochloride), Ellipticine HCl
Application:	Antitumor agent
CAS	5081-48-1
MW:	282.76 D

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Ellipticine (hydrochloride)

Item number: Cay18742-10

Ellipticine is an alkaloid isolated from Apocyanaceae plants that exhibits antitumor activities by intercalating into DNA and/or inhibiting DNA topoisomerase II. It forms covalent adducts in DNA after being enzymatically activated with cytochrome P450 isoforms (e.g., CYP3A4, CYP1A1, or CYP1A2) or by peroxidases in...

Keywords:	NSC 71795, 5,11-dimethyl-6H-pyrido[4,3-b]carbazole
Application:	Antitumor agent
CAS	5081-48-1
MW:	282.8 D

From 90.00€ *

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