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Item number: Cay17313-5

The transient receptor potential vanilloid type 1 (TRPV1) receptor is a nonselective cation channel gated by noxious heat, protons, and capsaicin (Cay-92350). SB-705498 is an orally bioavailable, competitive antagonist of the capsaicin-mediated activation of TRPV1 receptors (pKis = 7.6, 7.5, and 7.3 for human, rat,...

Keywords:	N-(2-bromophenyl)-N'-[(3R)-1-[5-(trifluoromethyl)-2-pyridinyl]-3-pyrrolidinyl]-urea
Application:	TRPV1 antagonist
CAS	501951-42-4
MW:	429.2 D

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SB-705498

Item number: TGM-T6660-100mg

Description: SB705498 is a TRPV1 antagonist for hTRPV1. SB-705498 has been investigated for the treatment of Rhinitis, Chronic Cough, and Non-allergic Rhinitis. Target: TRP/TRPV Channel. Smiles: FC(F)(F)c1ccc(nc1)N1CC[C@H](C1)NC(=O)Nc1ccccc1Br. References: Chen W T, Lin G B, Lin S H, et al. Static magnetic field...

Application:	TRPV1 antagonist
CAS	501951-42-4
MW:	429.23 D

From 39.00€ *

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