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Item number: Cay42544-10

Tie2/VEGFR2 kinase-IN-2 is an inhibitor of tunica interna endothelial cell kinase 2 (Tie2) and VEGFR2 (IC50s = 13. and 7. nM, respectively). It is selective for Tie2 and VEGFR2 over Akt3, cyclin-dependent kinase 2 (Cdk2), EGFR, and glycogen synthase kinase 3 (GSK3, IC50s = >10,000, >10,000, 10,000, and 2,187 nM,...

Keywords:	Tie2/Vascular Endothelial Growth Factor Receptor 2 Kinase Inhibitor 2, Tie2/Vascular Endothelial Growth Factor Receptor 2...
Application:	Tie2 / VEGFR inhibitor
CAS	501693-48-7
MW:	431.34 D

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