3 products were found matching "500579-04-4"!
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GANT 61
Item number: TGM-T3070-100mg
Description: GANT 61 (GANT61) is an inhibitor for Gli1 and Gli2. Target: Autophagy, Hedgehog/Smoothened. Smiles: CN(C)c1ccccc1CN1CCCN(Cc2ccccc2N(C)C)C1c1ccncc1. References: Lauth M, et al. Proc Natl Acad Sci, 2007, 104(20), 8455-8560
| Keywords: | NSC 136476, GANT61 |
| Application: | GLI antagonist |
| CAS | 500579-04-4 |
| MW: | 429.6 D |
From 34.00€
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GANT 61
Item number: Cay13841-10
Hedgehog proteins, important regulators of development, bind the cell-surface protein Patched, allowing activation of Smoothened. In vertebrates, this ultimately leads to the activation of the zinc-finger transcription factors of the Gli family. Overactivation of this pathway contributes to certain cancers,...
| Keywords: | NSC 136476, 2,2'-[[dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis(N,N-dimethyl-benzenamine) |
| Application: | GLI antagonist |
| CAS | 500579-04-4 |
| MW: | 429.6 D |
From 81.00€
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GANT61
Item number: AG-CR1-3561-M005
Cell permeable GLI antagonist. Inhibits Gli1 and Gli2-induced transcription. Hedgehog (Hh) signaling pathway inhibitor, downstream of SMO and SUFU. Displays antiproliferative and antitumor activity in vitro and in vivo. Apoptosis inducer.
| Keywords: | NSC 136476, 2,2'-((Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl)bis(methylene))bis(N,N-dimethyl)-benzenamine |
| Application: | GLI antagonist |
| CAS | 500579-04-4 |
| MW: | 429,6 D |
From 50.00€
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