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IP7e
Item number: Cay29726-1
IP7e is a brain-penetrant activator of nuclear receptor related protein 1 (Nurr1/NR4A2) signaling (EC50 = 3.9 nM in a reporter assay). In vivo, IP7e (10 mg/kg) prevents spinal cord axonal loss and demyelination and decreases spinal cord macrophage and T cell infiltration in a mouse model of experimental autoimmune...
| Keywords: | Isoxazolo-pyridinone 7e, 6-[4-[(2-methoxyethoxy)methyl]phenyl]-5-methyl-3-phenyl-isoxazolo[4,5-c]pyridin-4(5H)-one |
| Application: | Nurr1 signaling activator |
| CAS | 500164-74-9 |
| MW: | 390.4 D |
From 122.00€
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IP7e
Item number: TGM-T27620-100mg
Description: IP7e (isoxazolo-pyridinone 7e) is a Nurr1 activator with an EC50 value of 3.9 nM. Target: Others. Smiles: COCCOCc1ccc(cc1)-c1cc2onc(-c3ccccc3)c2c(=O)n1C. References: Montarolo F, et al. Effects of isoxazolo-pyridinone 7e, a potent activator of the Nurr1 signaling pathway, on experimental autoimmune...
| Keywords: | IP 7e, isoxazolo-pyridinone 7e, IP-7e |
| Application: | Nurr1 signaling activator |
| CAS | 500164-74-9 |
| MW: | 390.43 D |
From 110.00€
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