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DC_AC50
Item number: Cay19283-1
DC_AC50 is an inhibitor of the copper-trafficking proteins Atox1 and CCS. It binds to purified Atox1 and CCS (Kds = 6.8 and 8.2 µM, respectively) and inhibits the interaction between Atox1 and domain 4 of the Cu+-ATPase ATP7B in the presence of zinc in a FRET-based assay when used at a concentration of 100 µM....
| Keywords: | 3-amino-N-(2-bromo-4,6-difluorophenyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide |
| Application: | Atox1 / CCS inhibitor |
| CAS | 497061-48-0 |
| MW: | 424.3 D |
From 57.00€
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DC_AC50
Item number: TGM-T21876-100mg
Description: DC_AC50 is a dual inhibitor of Atox1 and CCS (copper chaperones), aimed at reducing or preventing acquired chemotherapy resistance by inhibiting intracellular copper chaperones. It binds to Atox1 and CCS, thereby reducing cancer cell proliferation and tumor growth. Target: Apoptosis, Others. Smiles:...
| CAS | 497061-48-0 |
| MW: | 424.26 D |
From 40.00€
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