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Item number: Cay43950-1

EN460 is an inhibitor of ERO1-like protein alpha (ERO1alpha, IC50 = 1. µM). It also inhibits additional FAD-containing enzymes, including monoamine oxidase A (MAO-A), MAO-B, and lysine-specific demethylase 1 (LSD1, IC50s = 7. 30. and 4. µM, respectively). EN460 (25 µM) induces endoplasmic reticulum (ER) stress and...

Keywords:	2-chloro-5-[4,5-dihydro-5-oxo-4-[(5-phenyl-2-furanyl)methylene]-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzoic acid
Application:	ERO1alpha inhibitor
CAS	496807-64-8
MW:	460.79 D

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