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Lipid-based Drug Delivery Tools from Cayman Chemical

Lipid-based drug delivery (LBDD) systems, such as LNPs, liposomes, and solid lipid nanoparticles (SLNs), are customizable platforms for the targeted delivery of pharmaceuticals and other therapeutic agents to cells and tissues. LBDD overcomes obstacles associated with conventional therapeutic formulations by encapsulating bioactive molecules in a lipid vesicle, which increases their bioavailability, distribution, and plasma half-life, and decreases systemic toxicity induced by off-target activity. The versatility of LBDD formulations is achievable in part through the diversity of lipids available for these applications. Our partner Cayman Chemical offers high-quality lipid components that can be used to build lipid particles as research tools, as well LNP Exploration Kits and Custom Lipid Synthesis to support preclinical research programs.

Learn more here:

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Blog Article: Lipid-based Drug Delivery Development - Part 1
Blog Article: Lipid-based Drug Delivery Development - Part 2
Caymans Guide to Lipid Nanoparticle Formulation

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Lipid-based Drug Delivery Tools

OH-C-Chol

Item number: Cay26587-1

OH-C-Chol is a cationic cholesterol derivative. OH-C-Chol, as a component of lipoplexes with DOPE (Cay-15091), has been used for siRNA delivery and gene silencing in MCF-7 cells as well as in mice via intravenous injection, resulting in lipoplex accumulation in the liver.Formal Name: (3beta)-cholest-5-en-3-ol...

Keywords:	(3beta)-cholest-5-en-3-ol 3-[N-[2-[(2-hydroxyethyl)amino]ethyl]carbamate]
Application:	Cationic cholesterol, SiRNA delivery
CAS	496801-51-5
MW:	516.8 D

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