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Item number: Cay13247-1

Eltrombopag is an orally bioavailable nonpeptide agonist of the thrombopoietin receptor (EC50 = 0.27 µM in a reporter assay) and an iron chelator. It increases STAT5 phosphorylation in N2C-Tpo cells when used at a concentration of 30 µM and p42/44 MAPK phosphorylation when used at 10 µM. Eltrombopag binds to the...

Keywords:	SB 497115,...
Application:	TpoR agonist
CAS	496775-61-2
MW:	442.5 D

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