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BI-0115
Item number: Cay43991-10
BI-0115 is an inhibitor of oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1). It inhibits oxidized LDL uptake in CHO cells expressing human Ox-LDL receptor 1 (IC50 = 5. µM). InChI: InChI=1S/C15H14ClN3O/c1-2-8-19-13-4-3-7-17-14(13)18-12-9-10(16)5-6-11(12)15(19)20/h3-7,9H,2,8H2,1H3,(H,17,18) InChIKey:...
| Keywords: | 9-chloro-5,11-dihydro-5-propyl-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one |
| Application: | Ox-LDL receptor 1 inhibitor |
| CAS | 4929-23-1 |
| MW: | 287.75 D |
From 325.00€
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BI-0115
Item number: TGM-T9108-100mg
Description: BI-0115 is a selective small molecule inhibitor of LOX-1 that blocks cellular uptake of oxLDL. It binding triggers receptor inhibition by formation of dimers of the homodimeric ligand binding domain. The structure of LOX-1 bound to BI-0115 shows that inter-ligand interactions at the receptor interfaces...
| CAS | 4929-23-1 |
| MW: | 287.74 D |
From 64.00€
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