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Item number: TGM-T2253-100mg

Description: TCS PIM-1 1 (SC 204330)(sc-204330) is an effective and specific ATP-competitive Pim-1 kinase inhibitor (IC50: 50 nM), exhibiting good specificity over MEK1/MEK2 and Pim-2 (IC50s > 20,000 nM). Target: Pim. Smiles: Oc1ccc(Br)cc1-c1cc(-c2ccccc2)c(C#N)c(=O)[nH]1. References: Cheney IW, et al. Bioorg Med...

Keywords:	SC 204330
Application:	PIM1 inhibitor
CAS	491871-58-0
MW:	367.2 D

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TCS PIM-1 1

Item number: Cay16286-10

The proto-oncogene serine/threonine-protein kinases, Pim-1 and Pim-2, are enzymes involved in cytokine signaling and participate in various signal transduction pathways, including cell growth, differentiation, and apoptosis. Their overexpression has been implicated in prostate cancer, some forms of leukemia, and...

Keywords:	Pim-1 Kinase Inhibitor II, SC-204330, 6-(5-bromo-2-hydroxyphenyl)-1,2-dihydro-2-oxo-4-phenyl-3-pyridinecarbonitrile
Application:	PIM1 inhibitor
CAS	491871-58-0
MW:	367.2 D

From 149.00€ *

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